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Research paper

Clinical approach to the diagnosis of autoimmune encephalitis in the pediatric patient

Pediatric-specific AE criteria. Three categories — possible AE, probable antibody-negative AE, definite antibody-positive AE. Incorporates EEG and developmental criteria.

Indexed context

Cellucci T, van Mater H, Graus F, et al.

seronegative-aepediatric-autoimmune-encephalitiscellucci-criteria

Markdown path

content/research/papers/2020-cellucci-pediatric-ae-criteria.md

Findings

Pediatric-specific AE criteria. Three categories — possible AE, probable antibody-negative AE, definite antibody-positive AE. Incorporates EEG and developmental criteria.

Why it may matter for Levi

Correct framework for evaluating the seronegative-AE hypothesis in Levi. His workup is incomplete under Cellucci criteria because CSF cytokines/AE panel/neopterin were not sent and infectious PCR on CSF is not documented.

Paper text

Clinical approach to the diagnosis of autoimmune encephalitis in the pediatric patient

Cellucci T, van Mater H, Graus F, et al. — Neurology Neuroimmunology & Neuroinflammation (2020). https://pubmed.ncbi.nlm.nih.gov/31953309/

Findings summary

Pediatric-specific AE criteria. Three categories — possible AE, probable antibody-negative AE, definite antibody-positive AE. Incorporates EEG and developmental criteria.

Relevance to Levi

Correct framework for evaluating the seronegative-AE hypothesis in Levi. His workup is incomplete under Cellucci criteria because CSF cytokines/AE panel/neopterin were not sent and infectious PCR on CSF is not documented.

Provenance

  • Ingested 2026-04-16 as part of the batch literature pass supporting the Root Cause Theories, diagnostics, and treatments workspaces.
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