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Research paper

Current and Future Treatment Strategies in DEE-SWAS — A Time for Precision Medicine?

Review arguing for a paradigm shift toward etiology-driven precision-medicine rather than syndrome-driven treatment; reports <33% of patients without cognitive sequelae under the classic syndrome-driven approach.

Indexed context

(2025 authors)

dee-swascswsprecision-medicinetreatment-review

Markdown path

content/research/papers/2025-dee-swas-treatment-strategies-review.md

Findings

Review arguing for a paradigm shift toward etiology-driven precision-medicine rather than syndrome-driven treatment; reports <33% of patients without cognitive sequelae under the classic syndrome-driven approach.

Why it may matter for Levi

Anchors the general argument that Levi's best long-term outcome depends on identifying and treating the underlying cause, not just suppressing spike-wave activity. Frames the genetic + CSF-inflammatory workup as part of the therapeutic plan, not separate from it.

Paper text

Current and Future Treatment Strategies in DEE-SWAS — A Time for Precision Medicine?

(2025 authors) — Seminars in Pediatric Neurology (2025). https://www.sciencedirect.com/science/article/abs/pii/S0887899425001869

Findings summary

Review arguing for a paradigm shift toward etiology-driven precision-medicine rather than syndrome-driven treatment; reports <33% of patients without cognitive sequelae under the classic syndrome-driven approach.

Relevance to Levi

Anchors the general argument that Levi's best long-term outcome depends on identifying and treating the underlying cause, not just suppressing spike-wave activity. Frames the genetic + CSF-inflammatory workup as part of the therapeutic plan, not separate from it.

Provenance

  • Ingested 2026-04-16 as part of the batch literature pass supporting the Root Cause Theories, diagnostics, and treatments workspaces.
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  • Companion memo: content/research/notes/2026-04-16-literature-pass.md